“MIT researchers have developed a way to make extremely high-resolution images of tissue samples, at a fraction of the cost of other techniques that offer similar resolution. The new technique relies on expanding tissue before imaging it with a conventional light microscope. Two years ago, the MIT team showed that it was possible to expand tissue volumes 100-fold, resulting in an image resolution of about 60 nanometers. Now, the researchers have shown that expanding the tissue a second time before imaging can boost the resolution to about 25 nanometers. This level of resolution allows scientists to see, for example, the proteins that cluster together in complex patterns at brain synapses, helping neurons to communicate with each other. It could also help researchers to map neural circuits, says Ed Boyden, an associate professor of biological engineering and brain and cognitive sciences at MIT.”
Related Content
Related Posts:
- MIT engineers 3D print the electromagnets at the heart of many electronics
- MIT scientists use a new type of nanoparticle to make vaccines more powerful
- Researchers discover new channels to excite magnetic waves with terahertz light
- Researchers harness 2D magnetic materials for energy-efficient computing
- This tiny, tamper-proof ID tag can authenticate almost anything
- Accelerating AI tasks while preserving data security
- Engineers develop an efficient process to make fuel from carbon dioxide
- New laser setup probes metamaterial structures with ultrafast pulses
- Physicists trap electrons in a 3D crystal for the first time
- Team engineers nanoparticles using ion irradiation to advance clean energy and fuel conversion