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Scientists program cells to remember and respond to series of stimuli

Synthetic biology allows researchers to program cells to perform novel functions such as fluorescing in response to a particular chemical or producing drugs in response to disease markers. In a step toward devising much more complex cellular circuits, MIT engineers have now programmed cells to remember and respond to a series of events. These cells can remember, in the correct order, up to three different inputs, but this approach should be scalable to incorporate many more stimuli, the researchers say. Using this system, scientists can track cellular events that occur in a particular order, create environmental sensors that store complex histories, or program cellular trajectories.”

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