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New microscope creates near-real-time videos of nanoscale processes

State-of-the-art atomic force microscopes (AFMs) are designed to capture images of structures as small as a fraction of a nanometer — a million times smaller than the width of a human hair. In recent years, AFMs have produced desktop-worthy close-ups of atom-sized structures, from single strands of DNA to individual hydrogen bonds between molecules. But scanning these images is a meticulous, time-consuming process. AFMs therefore have been used mostly to image static samples, as they are too slow to capture active, changing environments. Now engineers at MIT have designed an atomic force microscope that scans images 2,000 times faster than existing commercial models. With this new high-speed instrument, the team produced images of chemical processes taking place at the nanoscale, at a rate that is close to real-time video.”

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